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KMID : 0358420070500121679
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Korean Journal of Obstetrics and Gynecology
2007 Volume.50 No. 12 p.1679 ~ p.1684
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The normal range of amniotic fluid alpha-fetoprotein in singleton midtrimester pregnancy of Korean women
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Kim Jun-Hyung
Kim Haeng-Soo
Park Jin-Young
Ryu Hee-Sug
Byun Young-Ji
Yang Jeong-In
Park Jai-Sun
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Abstract
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Objective: To determine normal range of amniotic fluid alpha-fetoprotein (AFAFP) in midtrimester singleton Korean pregnant women whose pregnancy and neonatal outcomes were uneventful.
Methods: AFAFP levels were measured in midtrimester pregnancy during amniocentesis from May 1995 to September 2006 at tertiary referral center. Normal ranges were obtained from 954 singleton pregnancies in which pregnancy and neonatal outcomes were normal.
Results: Median values of AFAFP in midtrimester pregnancy were 15,800 ng/mL, 13,903.9 ng/mL, 11,408.7 ng/mL, 9,690.1 ng/mL, 6,923.4 ng/mL, 6,330.0 ng/mL, 5,295.3 ng/mL, 4,421.2 ng/mL, 3,162.5 ng/mL at 16 week, 17 week, 18 week, 19 week, 20 week, 21 week, 22 week, 23 week, and 24 week.
Conclusion:ONCLUSION: The normal range of AFAFP level in each gestational week in Korean women could be a good reference for prenatal diagnosis of various disorders.
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KEYWORD
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Amniotic fluid alpha-fetoprotein, AFAFP, midtrimester, normal range, singleton pregnancy, Korean women
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